Liberal glUcose Control in critically Ill patient with pre-existing type 2 Diabetes (LUCID): a phase IIB multi-centre parallel group randomised clinical trial
Associate Professor Adam DeaneFull Bio
The University of Melbourne
Austin Health; Melbourne Health; Northern Health; Peter MacCallum Cancer Centre; St Vincent’s Hospital Melbourne; Royal Women’s Hospital; Western Health
Project summaryDownload PDF
The Melbourne University Hospitals Group (Melbourne Health, Austin, St Vincent’s, Western and Northern hospitals), in collaboration with the Australian New Zealand Intensive Care Society Clinical Trials Group (ANZICS-CTG), will perform a pivotal multicentre randomised clinical trial to compare current treatment to a new approach, where blood glucose is treated only at a higher level in patients with diabetes. This trial will determine whether hypoglycaemia (low blood glucose) and other complications are less, resulting in better patients outcomes with this new approach.
This proposed intervention is inexpensive and, if effective, will transform the management of blood glucose in patients with type 2 diabetes who require admission to hospital.
Expansion activities include a nested cohort translational study testing the reliability of more accessible use point-of-care and continuous blood glucose monitoring. This will identify clinically important changes in blood sugar, enhancing broader community use of continuous and point-of-care testing.