The therapeutic impact of acute intermittent hypoxia on people with chronic spinal cord injury

Spinal cord injuries have a significant multisystem impact on function, respiratory capacity and quality of life. Therapeutic acute intermittent hypoxia is an emerging novel therapy to aid recovery after incomplete spinal cord injuries by enhancing neuroplasticity. Functional improvements have been demonstrated in animal models, and more recently, preliminary human clinical trials have shown Therapeutic acute intermittent hypoxia combined with task-specific training to be safe, feasible and potentially beneficial. I aim to explore whether therapeutic acute intermittent hypoxia can improve respiratory and functional outcomes for people living with spinal cord injury, with potential translation to other neuromuscular populations.