Establishing a stroke biobank to examine protein and genetic biomarkers for post-stroke cognitive decline in the Post Ischaemic Stroke Cardiovascular Exercise Study (PISCES)
Vascular brain burden is the greatest determinant of late-life cognition. People with stroke are at increased risk of cognitive decline and dementia, and yet are usually excluded from intervention studies. We need to target high-risk populations to reduce dementia risk and identify genetic and protein markers for post-stroke cognitive decline.